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Sunday, September 22, 2019

Strategies and Plans Adopted by Businesses in the Recession Essay Example for Free

Strategies and Plans Adopted by Businesses in the Recession Essay The long-term strategies and short-term plans adopted by businesses in the recession The recession has different impacts/effects on businesses/organizations as all businesses do not operate in the same market/sector. This causes the need for businesses to come up with strategies and plans for business survival. Strategies and plans adopted by businesses are tactics developed by businesses to aid them reach a particular goal/target. Plans adopted by businesses help them look ahead, focus on key points and prepare for opportunities and problems. Then strategies are developed to assist the aim of the plan to eliminate or reduce flaws to make sure the plan is carried out successfully. Burger King (BK) and McDonald’s (McD’s) although both operating in the restaurant/fast food market, they both dealt with the recession differently. BK planned to increase sales by drawing in more customers and survive through a pricing strategy change and investments. They sold some of their products at a loss in order to cope with the recession as consumers were looking for cheaper value meals. I think the purpose of this plan was to increase the profitability of the business. This forced competitors to sell their products at a loss to try and increase sales and stop BK from benefiting from the current recession as it has a well-known brand name which spelt trouble for smaller competitor businesses. BK’s low price strategy was heavily skewed towards poorer economic groups in the US who have been hit particularly badly by unemployment this made their prices reasonable and affordable by all income groups. Focusing on customers from the poorer economic group might have helped boost sales as they and other customers not hit by unemployment would be able to make purchases without great concern. As BK’s sales during the 2006 trading period was weak, they invested $3m to strengthen its UK operation and a marketing push has since paid off. Part of the investment was put towards the development of products which as a result Angus Burgers and the spiced up Angry Whopper were created. A spokesman said these products have played well which means their strategy worked and the investment wasn’t in vain as they achieved a 13% rise in quarterly profits to $50. 2m (? 31. 7m) as stated by guardian. co. uk. BK’s menu remains unchanged centred on burgers, fries and fizzy drinks trying to gain more sales from repeat customers. Being narrowly focused in the recession is not such a good idea as the whole economy is affected by the recession even though it has a greater impact on some groups. BK’s strategy is a dangerous strategy because they are relying heavily on old repeat customers. If those customers changed their taste, it would have a huge impact on BK’s sales and solutions to their situation could be being used by McDonalds leaving BK with no room to improve their performance. The best way to go about a situation like this is to focus on a strategy that would benefit and target everyone bearing in mind the areas which have been heavily affected to assist in controlling price levels. Using the full potential of the business/extension strategies could help save a business from a recession. This could create a loss in the short run but the business can recoup its costs in the long run if successful. However, McD’s approach to the current recession is different compared to the plans and strategies adopted by BK. BK is narrowly focused compared to McD’s as McD’s provides a variety of menus like the breakfast and the kids meal menu. McDs has diversified into salads, Panini’s and cappuccinos in the hope of satisfying so-called soccer mums which is a strategy to attracts more customers. By diversifying its products, McD’s is able to attract different types of customers like healthy eaters and regular caffeine takers. This expansion of product range strategy widens their target customers range allowing them to increase sales and market share. British Airways (BA) operating in the airline market tackles the recession completely different from McD’s and BK. During the recession, according to BA’s first half (April September) pre-tax profit and loss chart, their profits dropped dramatically from roughly ? 610m to ? 50m according to the chart given in the period 07/08 to 08/09 which is around the time the recession begun. They went on to make a further loss of ? 292 Million in the 09/10 period. This sparked a cause for concern. BAA adopted a short-term plan which was heavily centred on the workforce as the airport’s operator was believed to be overstaffed. They decided to reduce the number of staffs and advice some workers to work for free in order to cut labour cost expenditure (inc. Bonuses and allowances) to reduce the loss their making to stay in the competition. Chief executive Willie Walsh and 800 workers agreed to work for nothing voluntary in the month of July to help the company survive and reduce expenditure. This strategy although would help, it brings disadvantages. From this plan, their employer name brand will be affected as a lot of the staff will be unsatisfied causing the union to get involve and also affecting BAA’s operations which in turn affects their customers as the airline will not be operating effectively and running smoothly causing disturbances and leaving customers displeased. The recession causes businesses to come up with plans and strategies in order to survive and stay in the competition. BK, McD’s and BA all adapted different plans and strategies to survive. BK remained firmly rooted in their burgers, fries and fizzy drinks menu, reduced their pricing levels, invested in the launch of new products and marketing and also, targeted those hugely affected by the recession to gain sales by reducing their prices for some products for the population with a low income; charging both high and low prices in other words their pricing strategy was universal pricing (appealing to everyone upper, middle and lower class). Their rivals adopted a different strategy and plan although they both operate in the same market. McDonald’s diversified their products – introducing new products to target other types of consumers i. e. â€Å"soccer mums† as it already has menu’s which targets other consumers like children and healthy eaters. Also, they ran plenty of bargains and distributed gazillions of coupons which played a good part in their survival. BA was making a huge loss so they reduced the amount of employees as a means of cutting expenditure to help them survive. This strategy caused complications for their operations which left customers dissatisfied during the crisis and also the trade union decided to get involved as some of BA’s staff disagreed to the changes that was to take place.

Saturday, September 21, 2019

Comparison of Vietnamese and English Language: Idioms

Comparison of Vietnamese and English Language: Idioms Abstract Language is a system of communication of a nation. Every nation has their own historical, civilized, cultural, climatic characteristics, so every nation has their own language. However, different nations have similarities and differences in expressing their ideas. Studying similarities and differences between idioms of comparison in English and Vietnamese is liable to help the researcher to affirm that. Moreover, making some comparisons is a good way to memorize English idioms of comparison effectively and enjoyably. Hence, translation skill can be improved thanks to more knowledge about idioms. In addition, making comparisons between English and Vietnamese idioms can help the researcher to understand more about cultures of both of countries since similarities and differences in culture reflect coincidences and dissimilarities in ways of thinking and looking at the world of English and Vietnamese people. Idioms of comparison in Vietnamese and English:  A Contrastive Analysis Introduction Idioms of comparison are applied frequently in literature and in daily life. It serves as a tool to make the language more graphic. However, every language has differences in ways of expressing the same idea using idioms of comparison. The goal of the study is to discover some common types of comparison used in English and Vietnamese idioms. In addition, the study chiefly aims at finding out some similarities and differences between comparison idioms in both English and Vietnamese. Because there are so many comparison idioms in both languages, it is impossible to include all of them in the study. The study can just explore comparison idiomatic expressions which play an important part in the purpose of the study. Theoretical Framework Theoretical background of idioms in English Definition of idioms in English The Oxford Advanced Learners Dictionary defines idioms as: A group of words whose meaning is different from the meanings of the individual words (Hornby, 2006, p.740). The viewpoint is supported in A Dictionary of Linguistics Phonetics. The author regards an idiom as a term used in grammar and lexicography to refer to a sequence of words which us semantically and often syntactically restricted, so that they function as a single unit (Crystal, 1985, p.225). According to A Dictionary of Linguistics, an idiom is any expression peculiar to a language, conveying a distinct meaning, not necessarily explicable by, occasionally even contrary to, the general accepted grammatical rules (Pei Gaynor, 1954, p.95). Feature of English idioms When mentioning semantic features of idioms, we had better focus on the figurative meaning of idioms. It is the most important characteristic of idioms to know whether an expression is an idiom or not. According to Collins Cobuild English Language Dictionary: A idiom is a group of words which, when they are used together in a particular combination, has a different meaning from the one they would have if you took the meaning of the individual words in the group. (Sinclair, 1987, p.718) Smiley Goldtein (1998) also suggest that idioms are certainly more than the sums of their parts (p.76). That means the meaning of components of an idiom is different from the meaning of the whole idiom. That we can guess the meaning of an idiom or not depends on open or closed classes. As Yong and Peng (2007) suggest: In open class combinations, individual components are freely recombination and are used in a common literal sense. As co-occurrence of individual components is expected of this class of combinations, both their meaning and structures are predictable amenable to analysis. (p.178) For instance, we can guess the meaning of the idiom turn over a new leaf. Turn over means to make something change position so that the other side is facing towards the outside or the top and a new leaf is a leaf which is more beautiful, more perfect. Therefore, the meaning of the idioms can be guessed as to change your way of life to become a better, more responsible person. However, in close class combinations, we cannot guess the meaning of idioms. That is because they are characterized by semantic opaqueness, syntactic restrictions and structural stability (Yong Peng, 2007, p.178). For example, the idioms spread oneself too thin or for the birds. Idioms have a fixed form that usually cannot be changed (Heacock, 2003, p.ix). However, Heacock (2003) also claims: Not all fixed phrases are idioms. For example, close your eyes is a common fixed phrase, but not an idiom because each word in it is used in its standard meaning. The phrase keep your skirt is an idiom, however, because the phrase does not mean do not take off your skirt it means stay calm. (p.ix) Idioms can be divided into six different forms or structures: + Idioms located at noun entries such as in addition to', for the birdsà ¢Ã¢â€š ¬Ã‚ ¦ + Idioms located at verb entries such as look forward to, take off, hear aboutà ¢Ã¢â€š ¬Ã‚ ¦ + Idioms located at adjectival entries such as in short, hot under the collarà ¢Ã¢â€š ¬Ã‚ ¦ + Idioms located at adverbial entries such as once again, worse off à ¢Ã¢â€š ¬Ã‚ ¦ + Idioms located at pronominal entries such as give it up, come to nothingà ¢Ã¢â€š ¬Ã‚ ¦ + Idioms located at numeral entries such as give a hundred percent, one by oneà ¢Ã¢â€š ¬Ã‚ ¦ Its really important to know that modifying any components and functional words can lose the idiomatic meaning (Yong Peng, 2007). Theoretical background of idioms in Vietnamese Definition of idioms in Vietnamese According to Tà ¡Ã‚ »Ã‚ « Ä ià ¡Ã‚ »Ã†â€™n Thà  nh Ngà ¡Ã‚ »Ã‚ ¯ và   Tà ¡Ã‚ »Ã‚ ¥c Ngà ¡Ã‚ »Ã‚ ¯ Vià ¡Ã‚ »Ã¢â‚¬ ¡t Nam: Thà  nh ngà ¡Ã‚ »Ã‚ ¯ Tià ¡Ã‚ ºÃ‚ ¿ng Vià ¡Ã‚ »Ã¢â‚¬ ¡t là   nhà ¡Ã‚ »Ã‚ ¯ng tà ¡Ã‚ »Ã¢â‚¬ ¢ hà ¡Ã‚ »Ã‚ £p tà ¡Ã‚ »Ã‚ « ngà ¡Ã‚ »Ã‚ ¯ cà ¡Ã‚ »Ã¢â‚¬Ëœ đà ¡Ã‚ »Ã¢â‚¬ ¹nh cà ³ cà ¡Ã‚ ºÃ‚ ¥u trà ºc tà ¡Ã‚ »Ã‚ « hoà ¡Ã‚ ºÃ‚ ·c cà ¢u nhÆÂ °ng hoà  n toà  n thuà ¡Ã‚ »Ã¢â€ž ¢c phà ¡Ã‚ ºÃ‚ ¡m trà ¹ cà ¡Ã‚ ºÃ‚ ¥p tà ¡Ã‚ »Ã‚ «, Ä‘ÆÂ °Ãƒ ¡Ã‚ »Ã‚ £c mà £ hà ³a hà ¡Ã‚ ºÃ‚ §u hà ¡Ã‚ ºÃ‚ ¿t đà ¡Ã‚ »Ã‚ u cà ³ tà ­nh chà ¡Ã‚ ºÃ‚ ¥t cà ¡ch Ä‘ià ¡Ã‚ »Ã¢â‚¬ ¡u nghà ¡Ã‚ »Ã¢â‚¬ ¡ thuà ¡Ã‚ ºÃ‚ ­t, và   chà ¡Ã‚ »Ã¢â‚¬ ° là  m mà ¡Ã‚ »Ã¢â€ž ¢t thà  nh phà ¡Ã‚ ºÃ‚ §n trong cà ¢u nà ³i. (Nguyà ¡Ã‚ »Ã¢â‚¬ ¦n, 2010, p.5) As Nguyà ¡Ã‚ »Ã¢â‚¬ ¦n (2007) has noted in his book, thà  nh ngà ¡Ã‚ »Ã‚ ¯ là   tà ¡Ã‚ ºÃ‚ ­p hà ¡Ã‚ »Ã‚ £p tà ¡Ã‚ »Ã‚ « cà ¡Ã‚ »Ã¢â‚¬Ëœ đà ¡Ã‚ »Ã¢â‚¬ ¹nh đà £ quen dà ¹ng mà   nghÄ ©a cà ¡Ã‚ »Ã‚ §a nà ³ thÆÂ °Ãƒ ¡Ã‚ »Ã‚ ng khà ´ng thà ¡Ã‚ »Ã†â€™ già ¡Ã‚ ºÃ‚ £i thà ­ch Ä‘ÆÂ °Ãƒ ¡Ã‚ »Ã‚ £c mà ¡Ã‚ »Ã¢â€ž ¢t cà ¡ch Ä‘ÆÂ ¡n già ¡Ã‚ ºÃ‚ £n bà ¡Ã‚ ºÃ‚ ±ng nghÄ ©a cà ¡Ã‚ »Ã‚ §a cà ¡c tà ¡Ã‚ »Ã‚ « tà ¡Ã‚ ºÃ‚ ¡o nà ªn nà ³ (p. 8). Features of Vietnamese idioms Idioms are characterized by figurative and metaphorical meanings. Therefore, its too difficult to comprehend although we know the meanings of all their components. For example, là ¡Ã‚ ºÃ‚ ¥y thà ºng à ºp voi, gà   đà ¡Ã‚ »Ã†â€™ gà   cà ¡Ã‚ »Ã‚ ¥c tà ¡c, Ä‘i guà ¡Ã‚ »Ã¢â‚¬Ëœc trong bà ¡Ã‚ »Ã‚ ¥ngà ¢Ã¢â€š ¬Ã‚ ¦ Especially idioms are originated from fairy tales, folk talesà ¢Ã¢â€š ¬Ã‚ ¦such as ba que xà ¡Ã‚ »Ã‚  là ¡, thà ¡Ã‚ ºÃ‚ ±ng chà ¡Ã‚ ºÃ‚ ¿t cà £i thà ¡Ã‚ ºÃ‚ ±ng khià ªng, nà ¡Ã‚ »Ã‚ £ nhÆÂ ° chà ºa Chà ¡Ã‚ »Ã¢â‚¬ ¢m, sÆÂ ° tà ¡Ã‚ »Ã‚ ­ Hà   Ä Ãƒ ´ngà ¢Ã¢â€š ¬Ã‚ ¦ (Nguyà ¡Ã‚ »Ã¢â‚¬ ¦n, Nguyà ¡Ã‚ »Ã¢â‚¬ ¦n Phan, 2009). Idioms usually consist of more than 3 components whose counterpoint, alliteration and rhyme are combined with each other in many different ways. There are some idioms of comparison such as nà ³ng nhÆÂ ° là ¡Ã‚ »Ã‚ ­a, khà ³c nhÆÂ ° mÆÂ °a, nhanh nhÆÂ ° chà ¡Ã‚ »Ã¢â‚¬ ºpà ¢Ã¢â€š ¬Ã‚ ¦ Also, there are some idioms which are created according to counterpoint, alliteration such as tai to mà ¡Ã‚ ºÃ‚ ·t là ¡Ã‚ »Ã¢â‚¬ ºn, mià ¡Ã‚ »Ã¢â‚¬ ¡ng hà ¹m gan sà ¡Ã‚ »Ã‚ ©a, cà ¹ng hà ¡Ã‚ »Ã¢â€ž ¢i cà ¹ng thuyà ¡Ã‚ »Ã‚ n, ong bÆÂ °Ãƒ ¡Ã‚ »Ã¢â‚¬ ºm là ¡Ã‚ ºÃ‚ £ lÆÂ ¡ià ¢Ã¢â€š ¬Ã‚ ¦ Besides, some idioms are originally spoken words in everyday speech which are usually used again and again for a long time and then develop figurative meanings to become idioms, for instance chà ¡Ã‚ »Ã… ¸ cà ¡Ã‚ »Ã‚ §i và ¡Ã‚ »Ã‚  rà ¡Ã‚ »Ã‚ «ng, theo voi hà ­t bà £ mà ­a, nÆÂ °Ãƒ ¡Ã‚ »Ã¢â‚¬ ºc chà ¡Ã‚ ºÃ‚ £y chà ¡Ã‚ »- trÃ…Â ©ng, Ä‘i guà ¡Ã‚ »Ã¢â‚¬ Ëœc trong bà ¡Ã‚ »Ã‚ ¥ngà ¢Ã¢â€š ¬Ã‚ ¦ (Nguyà ¡Ã‚ »Ã¢â‚¬ ¦n et al, 2009). Theoretical background of English idioms of comparison At first, we should find out the definition of idioms of comparison which are also called similes. There are a lot of definitions of simile. According to Oxford Advanced Learners Dictionary, simile is a word or phrase that compares sth to sth else, using the words like or as, for example a face like a mask or as white as snow; the use of such words and phrases (Hornby, 2006, p.1369). An idiom of comparison is also defined as: the comparison of two nouns with different meanings, using the words like or as to make the connection. Friendship is like ice cream, fear moved like lighting, and leaves feel as slippery as fish are examples of similes. (Tucker, 2002, p.41) There is also a similar but shorter definition in The Challenge of Effective Speaking: A simile is a direct comparison of dissimilar things using the word like or as (Verderber, Verderber Sellnow, 2008, p.197). The meanings of similes are figurative. Take the simile as tall as a tree as an example. When you say: Minh is as stubborn as a mule, you mean Minh is so stubborn, not Minh is as stubborn as a mule. Therefore, the simile as stubborn as a mule is considered figurative. Learners can sometimes be confused between similes and metaphors but they are really different: A metaphor, like a simile, is a comparison between two essentially unlike things. In contrast to a simile, however, where an explicit comparison is made (The eye is like a lamp for the body), the metaphor makes an implicit comparison (The eye is lamp of the body). (Robert H. Stein 15) Huff (2004) asserts that the only difference between simile and metaphor is that metaphor does not use the words like or as to make the comparison (p.98). In other words, two distinctly different things in a simile are connected by like or as while a metaphor is an implied but in many ways even more direct than comparison because the reader is expected to identify the comparison without the word like or as (Osborne, 1997, p.124). However, because similes merely join two disparate ideas or images, they are generally less fertile than metaphors, which can evoke additional and fresh shades of meaning (Ehrenhaft, 2008, p.145). Theoretical background of Vietnamese idioms of comparison In Vietnamese, there are 2 kinds of idioms of comparison: one employs the word nhÆÂ °, tà ¡Ã‚ »Ã‚ ±a, tà  y, bà ¡Ã‚ ºÃ‚ ±ng, tà ¡Ã‚ »Ã‚ ±a nhÆÂ ° or cÃ…Â ©ng nhÆÂ ° and one doesnt. Based on similarities of characteristics of 2 things, 2 phenomena, 2 actions, the Vietnamese create a large number of idioms which use A to name or to modify B. Eg: Mà ¡Ã‚ ºÃ‚ ·t trà ¡i xoan: oval-shaped face. Star: a famous and talented person (usually in art, sport, culture). (Nguyà ¡Ã‚ »Ã¢â‚¬ ¦n, 2010) The other kind of idioms of comparison includes the word bà ¡Ã‚ ºÃ‚ ±ng, tà  y, tà ¡Ã‚ »Ã‚ ±a, sà ¡nh, nhÆÂ ° or cÃ…Â ©ng nhÆÂ ° which divides an idiom into 2 parts. Both of parts can be a noun, verb, phrase or clause. The second part whose function is predicating and complementing the first part is counted from comparative word. Eg: In the idiom tà ¡Ã‚ »Ã¢â€ž ¢i tà  y đà ¬nh, tà  y đà ¬nh is the complement of the noun tà ¡Ã‚ »Ã¢â€ž ¢i. In the idiom chà ¡Ã‚ ºÃ‚ ¡y nhÆÂ ° bay, nhÆÂ ° bay is the complement of the verb chà ¡Ã‚ ºÃ‚ ¡y. (Nguyà ¡Ã‚ »Ã¢â‚¬ ¦n, 2010) A contrastive analysis of comparison idioms in English and Vietnamese Quantity comparison There are about 700 idioms of comparison in English, for example, as warm as sunbeam, to follow like a shadow, to work like a Trojan,à ¢Ã¢â€š ¬Ã‚ ¦ There are a similarity in the number of idioms of comparison in English and Vietnamese. Some examples of Vietnamese idioms of comparison are là ¡Ã‚ ºÃ‚ ¡nh nhÆÂ ° tià ¡Ã‚ »Ã‚ n, xanh nhÆÂ ° tà  u là ¡Ãƒ ¢Ã¢â€š ¬Ã‚ ¦ Similarities of idioms of comparison in English and Vietnamese Although the culture of two nations is different, ways of thinking and looking at the world of English and Vietnamese is somehow similar. Hence, both Vietnamese and English express ideas and concepts in the same way. In fact, a large number of Vietnamese idioms of comparison are similar with English idioms of comparison in terms of both concept and image to express. English idioms Vietnamese idioms As black as coal Ä en nhÆÂ ° than As black as crow Ä en nhÆÂ ° quà ¡Ã‚ ºÃ‚ ¡ As black as ink Tà ¡Ã‚ »Ã¢â‚¬Ëœi Ä‘en nhÆÂ ° mà ¡Ã‚ »Ã‚ ±c As sweet as sugar Ngà ¡Ã‚ »Ã‚ t nhÆÂ ° Ä‘ÆÂ °Ãƒ ¡Ã‚ »Ã‚ ng As black as soot Ä en nhÆÂ ° bà ¡Ã‚ »Ã¢â‚¬Å" hà ³ng As brief as a dream Ngà ¡Ã‚ ºÃ‚ ¯n nhÆÂ ° mà ¡Ã‚ »Ã¢â€ž ¢t già ¡Ã‚ ºÃ‚ ¥c mà ¡Ã‚ »Ã¢â€ž ¢ng As bright as day Sà ¡ng nhÆÂ ° ban ngà  y As brilliant as stars Sà ¡ng nhÆÂ ° sao As changeable as the weather Hay thay đà ¡Ã‚ »Ã¢â‚¬ ¢i nhÆÂ ° thà ¡Ã‚ »Ã‚ i tià ¡Ã‚ ºÃ‚ ¿t As cold as ice Là ¡Ã‚ ºÃ‚ ¡nh nhÆÂ ° băng As cheerful as a lark Vui nhÆÂ ° sà ¡o As cunning as a fox Xà ¡Ã‚ ºÃ‚ £o quyà ¡Ã‚ »Ã¢â‚¬ ¡t nhÆÂ ° cà ¡o As dark as midnight Tà ¡Ã‚ »Ã¢â‚¬Ëœi nhÆÂ ° nà ¡Ã‚ »Ã‚ ­a đà ªm As dumb as a an oyster Cà ¢m nhÆÂ ° hà ¡Ã‚ ºÃ‚ ¿n As fair as a rose Xinh nhÆÂ ° hoa As fast as a hare Nhanh nhÆÂ ° thà ¡Ã‚ »Ã‚  As fat as a pig Mà ¡Ã‚ ºÃ‚ ­p nhÆÂ ° heo As fierce as a tiger Dà ¡Ã‚ »Ã‚ ¯ nhÆÂ ° cà ¡Ã‚ »Ã‚ p As firm as rock Và ¡Ã‚ »Ã‚ ¯ng nhÆÂ ° đà ¡ As fleet as the wind Nhanh nhÆÂ ° già ³ As fresh a rose TÆÂ °Ãƒâ€ Ã‚ ¡i nhÆÂ ° hoa As gay as a lark Vui nhÆÂ ° sà ¡o As gruff as a bear Hà ¡Ã‚ »-n nhÆÂ ° gà ¡Ã‚ ºÃ‚ ¥u As good (valuable) as gold Quà ½ nhÆÂ ° và  ng As green as a leaf Xanh nhÆÂ ° tà  u là ¡ As heavy as an elephant Nà ¡Ã‚ ºÃ‚ ·ng nhÆÂ ° voi As hard as a stone Cà ¡Ã‚ »Ã‚ ©ng nhÆÂ ° đà ¡ As heavy as lead Nà ¡Ã‚ ºÃ‚ ·ng nhÆÂ ° chà ¬ As hot as fire Nà ³ng nhÆÂ ° là ¡Ã‚ »Ã‚ ­a As keen as a razor Sà ¡Ã‚ ºÃ‚ ¯c nhÆÂ ° dao cà ¡Ã‚ ºÃ‚ ¡o As light as down Nhà ¡Ã‚ ºÃ‚ ¹ tà ¡Ã‚ »Ã‚ ±a là ´ng hà ¡Ã‚ »Ã¢â‚¬Å"ng As light as a feather Nhà ¡Ã‚ ºÃ‚ ¹ tÆÂ °a là ´ng hà ¡Ã‚ »Ã¢â‚¬Å"ng As mum as an oyster Cà ¢m nhÆÂ ° hà ¡Ã‚ ºÃ‚ ¿n As pretty as a picture Ä Ãƒ ¡Ã‚ ºÃ‚ ¹p nhÆÂ ° tranh As quick as lightning Nhanh nhÆÂ ° à ¡nh sà ¡ng As quick as a flash Nhanh nhÆÂ ° chà ¡Ã‚ »Ã¢â‚¬ ºp As red as blood Ä Ãƒ ¡Ã‚ »Ã‚  nhÆÂ ° mà ¡u As red as a beetroot Ä Ãƒ ¡Ã‚ »Ã‚  nhÆÂ ° gà ¡Ã‚ ºÃ‚ ¥c As sharp as a razor Sà ¡Ã‚ ºÃ‚ ¯c nhÆÂ ° dao cà ¡Ã‚ ºÃ‚ ¡o As silly as a calf Ngu nhÆÂ ° bà ² As sour as vinegar Chua nhÆÂ ° già ¡Ã‚ ºÃ‚ ¥m As stink as a polecat Hà ´i nhÆÂ ° chà ¡Ã‚ »Ã¢â‚¬Å"n As swift as lightning Nhanh nhÆÂ ° chà ¡Ã‚ »Ã¢â‚¬ ºp As smooth as velvet Mà ¡Ã‚ »Ã¢â‚¬ ¹n nhÆÂ ° nhung As slow as a snail Chà ¡Ã‚ ºÃ‚ ­m nhÆÂ ° sà ªn As swift as an arrow Nhanh nhÆÂ ° tà ªn bà ¡Ã‚ ºÃ‚ ¯n As steady as rock Cà ¡Ã‚ »Ã‚ ©ng nhÆÂ ° đà ¡ As timid as a rabbit/ hare Nhà ¡t nhÆÂ ° thà ¡Ã‚ »Ã‚  đà ¡Ã‚ ºÃ‚ ¿ As thick as ants Ä Ãƒ ´ng nhÆÂ ° kià ¡Ã‚ ºÃ‚ ¿n As transparent as glass Trong suà ¡Ã‚ »Ã¢â‚¬Ëœt nhÆÂ ° thà ¡Ã‚ »Ã‚ §y tinh As yellow as saffron Và  ng nhÆÂ ° nghà ¡Ã‚ »Ã¢â‚¬ ¡ As wet as a drowned mouse ÆÂ ¯Ãƒ ¡Ã‚ »Ã¢â‚¬ ºt nhÆÂ ° chuà ¡Ã‚ »Ã¢â€ž ¢t là ¡Ã‚ »Ã¢â€ž ¢t As white as snow Trà ¡Ã‚ ºÃ‚ ¯ng nhÆÂ ° tuyà ¡Ã‚ ºÃ‚ ¿t As white as a sheet NhÆÂ ° tà ¡Ã‚ »Ã‚  già ¡Ã‚ ºÃ‚ ¥y trà ¡Ã‚ ºÃ‚ ¯ng Like father like son Cha nà  o con nà ¡Ã‚ ºÃ‚ ¥y To fight like cat and dog NhÆÂ ° chà ³ và ¡Ã‚ »Ã¢â‚¬ ºi mà ¨o To stick like a leech Bà ¡m dai nhÆÂ ° đà ¡Ã‚ »Ã¢â‚¬ °a To stick like glue Dà ­nh nhÆÂ ° keo To cry like a baby Khà ³c nhÆÂ ° đà ¡Ã‚ »Ã‚ ©a trà ¡Ã‚ ºÃ‚ » To follow like a shadow Theo nhÆÂ ° hà ¬nh và ¡Ã‚ »Ã¢â‚¬ ºi bà ³ng To swim like fish BÆÂ ¡i nhÆÂ ° cà ¡ Differences of idioms of comparison in English and Vietnamese The same content but different images to express Images of idiomatic comparisons in twp nations are different result from differences in culture. Vietnam has the cultural tradition of the wet rice production. Therefore, animals have a strong attachment to Vietnamese daily life. Thats why Vietnamese idioms of comparison consist of images related to buffaloes which are an animal familiar with rice production agriculture. Buffaloes pull ploughs, work very hard everyday to help farmers in their farming. As a result, wanting to mention strength, people often refer to buffaloes. In fact, to talk about someone very strong, the Vietnamese have the idiom khà ¡Ã‚ »Ã‚ e nhÆÂ ° trà ¢u while the English have the idiom as strong as a horse. Thats because English people prefer horses to buffaloes. Horses can not only pull ploughs but also transport and entertain. They are really energetic and strong enough to help people in life. In spite of that, it doesnt mean that English people dont consider buffaloes strong animals or Vietnamese people dont regard horses as strong animals. That results just from the difference in culture. Also, dragons are a kind of animal which is very close in fertile imagination of Vietnamese people. Because of that, the image as a dragon appear in the Vietnamese idiom of comparison ăn nhÆÂ ° rà ¡Ã‚ »Ã¢â‚¬Å"ng cuà ¡Ã‚ »Ã¢â‚¬Ëœn to talk about eating large quantities of food while the image of a horse is used in the idiom to eat like a horse. Lamp, butter are so familiar with English life while sweet potatoes, pig are familiar with Vietnamese life, as a result there are differences in images to express their ideas of gentleness and fatness: English idioms Vietnamese idioms As gentle as a lamp Hià ¡Ã‚ »Ã‚ n nhÆÂ ° cà ¡Ã‚ »Ã‚ § khoai As fat as butter Bà ©o nhÆÂ ° là ¡Ã‚ »Ã‚ £n Besides, the differences in the ways of thinking and observing the world make differences in the images of idiomatic comparisons. Take some following examples to illustrate that: English idioms Vietnamese idioms As easy as ABC Dà ¡Ã‚ »Ã¢â‚¬ ¦ nhÆÂ ° trà ¡Ã‚ »Ã… ¸ bà  n tay As easy as pie Dà ¡Ã‚ »Ã¢â‚¬ ¦ nhÆÂ ° trà ¡Ã‚ »Ã… ¸ bà  n tay As easy as anything Dà ¡Ã‚ »Ã¢â‚¬ ¦ nhÆÂ ° trà ¡Ã‚ »Ã… ¸ bà  n tay As smooth as butter MÆÂ °Ãƒ ¡Ã‚ »Ã‚ £t nhÆÂ ° nhung As pale as a ghost Xanh nhÆÂ ° tà  u là ¡ As lazy as a lizard LÆÂ °Ãƒ ¡Ã‚ »Ã‚ i nhÆÂ ° hà ¡Ã‚ »Ã‚ §i As soft as wax Mà ¡Ã‚ »Ã‚ m nhÆÂ ° bà ºn As merry as a cricket Vui nhÆÂ ° tà ¡Ã‚ ºÃ‚ ¿t As cheerful as the birds Vui nhÆÂ ° tà ¡Ã‚ ºÃ‚ ¿t As glad as a fly Vui nhÆÂ ° tà ¡Ã‚ ºÃ‚ ¿t As happy as a child Vui nhÆÂ ° tà ¡Ã‚ ºÃ‚ ¿t As happy as a clam Vui nhÆÂ ° tà ¡Ã‚ ºÃ‚ ¿t As dark as midnight Tà ¡Ã‚ »Ã¢â‚¬Ëœi nhÆÂ ° đà ªm ba mÆÂ °Ãƒâ€ Ã‚ ¡i As black as midnight Tà ¡Ã‚ »Ã¢â‚¬Ëœi nhÆÂ ° đà ªm 30 As dark as midnight Tà ¡Ã‚ »Ã¢â‚¬Ëœi nhÆÂ ° hÃ…Â © nà ºt As close as herrings Chà ¡Ã‚ ºÃ‚ ·t nhÆÂ ° nà ªm As soundly as a log (Ngà ¡Ã‚ »Ã‚ §) say nhÆÂ ° chà ¡Ã‚ ºÃ‚ ¿t As cold as marble Là ¡Ã‚ ºÃ‚ ¡nh nhÆÂ ° tià ¡Ã‚ »Ã‚ n As dry as a biscuit Khà ´ nhÆÂ ° ngà ³i As red as lipstick Ä Ãƒ ¡Ã‚ »Ã‚  nhÆÂ ° gà ¡Ã‚ ºÃ‚ ¥c As thin as finger Gà ¡Ã‚ ºÃ‚ §y nhÆÂ ° bà ¡Ã‚ »Ã¢â€ž ¢ xÆÂ °Ãƒâ€ Ã‚ ¡ng khà ´ As weak as a kitten Yà ¡Ã‚ ºÃ‚ ¿u nhÆÂ ° sà ªn As weak as a baby Yà ¡Ã‚ ºÃ‚ ¿u nhÆÂ ° sà ªn As black as a stack of black cats Ä en nhÆÂ ° cà ¡Ã‚ »Ã¢â€ž ¢t nhà   chà ¡y As black as the ace of spades Ä en nhÆÂ ° cà º sà ºng As round as a barrel Trà ²n nhÆÂ ° quà ¡Ã‚ ºÃ‚ £ bà ³ng As old as the hills XÆÂ °a nhÆÂ ° trà ¡i đà ¡Ã‚ ºÃ‚ ¥t As hot as mustard Cay nhÆÂ ° à ¡Ã‚ »Ã¢â‚¬ ºt Like hot cake Ä Ãƒ ¡Ã‚ ºÃ‚ ¯t nhÆÂ ° tà ´m tÆÂ °Ãƒâ€ Ã‚ ¡i As silent as the dead Im là ¡Ã‚ ºÃ‚ ·ng nhÆÂ ° tà ¡Ã‚ »Ã‚  As silent as the grave Im là ¡Ã‚ ºÃ‚ ·ng nhÆÂ ° tà ¡Ã‚ »Ã‚  What is more, the differences in human make differences between English and Vietnamese idioms. For example, in Vietnam, there is the idiom ghen nhÆÂ ° Hoà ¡Ã‚ ºÃ‚ ¡n ThÆÂ ° to refer to a person who is dreadfully jealous. However, in English, the idiom as jealous as Othello is used to talk about a ones jealousy. Another example is sÆÂ °Ãƒ ¡Ã‚ »Ã¢â‚¬ ºng nhÆÂ ° tià ªn and as happy as a king. Indeed, Vietnamese people consider a fairy the happiest one while English people consider a king the happiest one. The same components but the dissimilar content Every so often, some images of comparison can appear in both Vietnamese and English idioms but the meaning of the two whole idioms are quite different. Thats because the meaning of components differs in culture. Indeed, using the idiom rà µ nhÆÂ ° ban ngà  y, the Vietnamese want to indicate a event which has nothing fishy. Meanwhile English people use the idiom as bright as day to describe a light room. Besides, when the weather is fine and sunny with good natural light, English people say: Its as bright as day. Besides, wanting to compliment someone on his or her beauty of eyes, Vietnamese people say: Mà ¡Ã‚ ºÃ‚ ¯t cà ´ sà ¡Ã‚ ºÃ‚ ¯c nhÆÂ ° dao cà ¡Ã‚ ºÃ‚ ¡o. Still, English people use the idiom as sharp as a razor to refer to ones brainpower. What is more, whilst Vietnamese people apply the idiom chà ¡Ã‚ ºÃ‚ ¯c nhÆÂ ° Ä‘inh đà ³ng cà ¡Ã‚ »Ã¢â€ž ¢t to something steady, as hard as nails in English idiom means a person who is quite strict. Also, when Vietnamese people say: Nà ³ tà ¡Ã‚ »Ã¢â‚¬Ëœt nhÆÂ ° và  ng, they mean its worth buying the object because of its good quality. In contrast, as good as gold cannot be used to compliment an object. In other words, English people never say: Its as good as gold but The person is as good as gold. The person can be an assiduous and submissive child or a well-behaved adult. Pedagogical Implications for Teaching English Idioms of comparison Learning English idioms is one of steps so as to help learners master English. English idioms of comparison are frequently used in daily life. Therefore, teachers should help their students learn idioms most effectively. Firstly, its advisable for teachers to raise students awareness of similarities and differences between Vietnamese and English idioms of comparison. When teachers teach their students a certain English idiom of comparison, they should let them guess the Vietnamese idiom which is equivalent to that idiom, making a comparison and explain why they are similar or different. Its really useful for them to have a long-term memory about that idiom of comparison. Secondly, idioms of comparison as well as other idioms are taught and practiced in classroom but students rarely apply them to their daily speech. Thats why teachers should encourage students to use idioms of comparison in their daily life as frequently as possible. Learners will memorize idioms better if idioms of comparison are put into communicative contexts. Dont make them learn by heart. Thirdly, teachers should draw students attention to idioms of comparison which are most useful and most frequent. As there are so many idioms of comparison in English culture, about 700, students arent liable to memorize and apply all of them in their daily life. Students should be taught to know what idioms of comparison they should learn. Conclusion There are both similarities and differences between English and Vietnamese idioms of comparison. The same or different image can bear resemblance in the meaning of English and Vietnamese idioms of comparison. In addition, there are some idioms of comparison which have the same components but the meaning are quite different. Great as have the researcher made an attempt to do the research, there are some restrictions on the research out of the limited time and other unexpected factors. The researcher hopes that the research will a useful material for learners and teachers to learn or teach most effectively.

Friday, September 20, 2019

Estimation of Salbutamol Sulphate and Guaiphenesin

Estimation of Salbutamol Sulphate and Guaiphenesin SIMULTANEOUS ESTIMATION OF SALBUTAMOL SULPHATE AND GUAIPHENESIN IN THEIR COMBINED LIQUID DOSAGE FORM BY HPTLC METHOD Kruti D. Bhalara, Ishwarsingh S. Rathod, Sindhu B. Ezhava, Dolarrai D. Bhalara, ABSTRACT A simple, specific, sensitive and validated high-performance thin layer chromatographic (HPTLC) method was developed for the simultaneous analysis of Salbutamol sulphate and Guaiphenesin. Spectro-densitometric scanning-integration was performed at an absorbance wavelength 280 nm. A TLC aluminium sheet pre coated with silica gel 60 F254 was used as the stationary phase. The mobile phase system containing Ethyl acetate: Methanol: Ammonia (25% w/v) (75: 15: 10 v/v) gave a good resolution of Salbutamol sulphate and Guaiphenesin with Rf values of 0.47 and 0.65, respectively. The calibration plot of Salbutamol sulphate exhibited good linear regression relationship (r = 0.9987) over a concentration range of 200-1000 ng/spot. The calibration plot of Guaiphenesin exhibited good polynomial regression relationship (r = 0.9997) over a concentration range of 10-50 ÃŽ ¼g/spot. Detection and quantitation limit was found to be 70 ng and 100 ng respectively, for Salbutamol sulphate and 30 ng and 50 n g, for Guaiphenesin. The proposed method was used for determination of both drugs in Ventorlin and Asthalin Syrup containing Salbutamol sulphate and Guaiphenesin with satisfactory precision (Intraday) [2.67-4.46% for Salbutamol sulphate and 2.39-4.42% for Guaiphenesin] and accuracy [100.97 ± 0.50% and 100.45  ± 0.58% RSD, for Salbutamol sulphate and Guaiphenesin respectively] INTRODUCTION Salbutamol sulpahte (SAL) is the selective prototypic ÃŽ ²2-adrenoceptor agonist. It is used as an anti-asthmatic in the treatment of bronchial asthma, bronchospasm, in the patients with reversible obstructive airway and in prevention of exercise induced bronchospasm(1-3). It may be used in uncomplicated premature labour. SAL is chemically (RS)-1-(4-hydroxy-3-hydroxy- methyl phenyl)-2-(tert-butyl amino) ethanol sulphate(2, 3). Guaiphenesin (GUA) is used as an expectorant in the symptomatic management of coughs associated with the common cold, bronchitis, pharyngitis, influenza, measles etc(1-3). It is chemically (RS)-3-(2-methoxyphenoxy)-1,2- propanediol(2, 3). SAL and GUA combinations are available in the market for the respiratory disorders where bronchospasm and excessive secretion of tenacious mucus are complicating factors, for example bronchial asthma, chronic bronchitis emphysema. Chemical structures of GUA and SAL are shown in Figure 1. SAL (API) is official in the Indian Pharmacopoeia(2), British Pharmacopoeia(4), and US Pharmacopoeia(5), and SAL syrup and tablets are official in British Pharmacopoeia(4). GUA (API) is official in the Indian Pharmacopoeia(2), British Pharmacopoeia(4), and US Pharmacopoeia(5), and GUA tablets, capsules and injection are also official in US Pharmacopoeia(5). However, the combination of SAL and GUA is not official in any pharmacopoeia. Several methods have been reported in literature for individual estimation of the drugs but very few methods have been reported for simultaneous estimation of SAL and GUA in combined dosage form, which includes chemo metrics-assisted spectrophotometry(6), Electro kinetic chromatography and Gas chromatography-Mass spectrometry(7) and Micellar electrokinetic chromatography(8). HPLC, though accurate and precise method, is time consuming, costly and requires skilled operator. Therefore the aim of this study was to develop and validate simple, specific, inexp ensive, rapid, accurate and precise High Performance Thin Layer Chromatography (HPTLC) method for simultaneous estimation of SAL and GUA in their combined dosage form. The proposed method was successfully applied to two marketed cough syrups Ventorlin ® and Asthalin ® and the contents were determined without any interference of excipients. MATERIALS Reagents and Materials (a) Solvents: Analytical reagent grade Ethyl acetate (Finar Chemicals, India) and methanol (RFCL Limited, India) and ammonia (25% w/v) (s. d. Fine Chem Limited, India); Iso propyl alcohol (s. d. Fine Chem Limited, India); Sodium bicarbonate (s. d. Fine Chem Limited, India) (b) Standards: SAL and GUA were a gift sample from Preet Pharma, Gujarat, India. (c) Ventorlin ® syrup (GSK Pharmaceutical Ltd, India) – Batch 02053, labeled 2 mg SAL and 100 mg GUA in each 5 ml of syrup, were purchased commercially. (d) Asthalin ® syrup (Cipla Pharmaceuticals, Mumbai, India) – Batch 060305, labeled 2 mg SAL and 100 mg GUA in each 5 ml of syrup, were purchased commercially. Apparatus (a) HPTLC Plate: 20Ãâ€"20cm, percolated with silica gel 60 F254, 0.2 mm layer thickness ( E.Merck, Germany) (b) Spotting device: Linomat IV Semiautomatic sample applicator (Camag, Switzerland) (c) Chamber: Twin trough chamber for 20 Ãâ€" 10 cm (Camag) (d) Densitometer: TLC Scanner-3 linked to win CATS software (Camag). Scanner mode- absorbance-reflectance; Scanning Wavelength: 280 nm; lamp: Deuterium; measurement type: remission; measurement mode: absorption; detection mode: automatic. Scanner setting- Slit dimension: 3.00 Ãâ€" 0.1 mm (e) Syringe: 100  µl (Hamilton, Switzerland) (f) Analytical balance: Shimandzu Libror AEG – 220 balances METHODS Preparation of SAL and GUA standard solutions Stock solution of SAL (equivalent to 2 mg/ml) was prepared by dissolving 20 mg SAL pure substance in 10 ml methanol. Working stock solution of SAL (equivalent to 0.2 mg/ml) was prepared by transferring 1.0 ml of above stock solution in 10.0 ml methanol. Stock solution (10 mg/ml) of GUA was prepared by dissolving 100 mg GUA pure substance in 10.0 ml methanol, separately. These solutions were stored under refrigeration at 40C. A mixture of the drugs was prepared by transferring 1.0 ml of stock solutions of each compound to 10 ml volumetric flask and diluting to volume with methanol. (Final concentrations of SAL, 0.02 mg/ml and GUA, 1 mg/ml) Preparation of calibration curve 10-50 micro liters of standard solutions of combined standard solution of SAL (0.2, 0.4, 0.6, 0.8 and 1.0  µg/spot) and GUA (10, 20, 30, 40, and 50  µg/spot) and 2 sample solutions (20  µl; corresponding to 0.4  µg SAL and 20  µg GUA/spot) were applied onto a pre coated HPTLC plate using the semiautomatic sample spotter (bandwidth: 3 mm, distance between the tracks: 5 mm). The plate was developed to a distance of 45 mm in a HPTLC chamber containing the mobile phase, i.e., Ethyl acetate-methanol-ammonia (7.5+1.5+1.0 v/v/v), at 25  ± 2 0C. The plate was dried at room temperature. The substances on the silica gel layer were identified densitometrically at 280 nm. The chromatograms were scanned at 280 nm with slit dimensions of 0.1 mm Ãâ€" 3 mm; 400 nm was used as the reference wavelength for all measurements. Concentrations of the compounds chromatographed were determined from changes in the intensity of diffusely reflected light. Evaluation was via peak area with linear re gression for SAL and polynomial regression for GUA. Preparation of sample solutions A 5 ml aliquot of the Commercial syrup (Ventorlin ® or Asthalin ®) was transferred into 10 ml volumetric flask. The volume was adjusted with methanol. From this solution, 2 ml was pipetted and transferred into another 10 ml volumetric flask. The volume was adjusted to the mark with methanol. The methanolic solution was used for chromatographic analysis. (SAL 20 ÃŽ ¼g/ml and GUA 1 mg/ml) Method validation The method was validated in compliance with International Conference on Harmonization guidelines(9). (a) Specificity._ The specificity of the method was established by comparing the chromatograms and measuring the peak purities of SAL and GUA from standard and sample solutions of liquid dosage forms. The peak purity of SAL and GUA were assessed by comparing spectra obtained at the peak start (S), peak middle (M) and peak end (E) of a spot. Correlation between SAL and GUA spectra from standard and sample was also obtained. (b) Accuracy._ The accuracy of the method was determined by standard addition method and calculating the recoveries of SAL and GUA . Prequantified sample stock solution of SAL and GUA ( 1 mL equivalent to 200 µG/ml of SAL and 10mg/ml of GUA) was transferred into a series of 10 mL volumetric flasks. Known amounts of standard stock solution of SAL(0, 1,2 and 3 mL equivalent to 200, 400, 600 ng/spot ) and GUA ( 0, 1, 2 and 3 mL equivalent to 0, 10,20 and 30  µg/spot) were added to this prequantified working sample solutions and diluted up to the mark with methanol. Each solution (10  µL) was applied on plates in triplicate. The plates were developed and scanned as described above, and the recovery was calculated by measuring the peak areas and fitting these values into the regression equation of the calibration curves. (c) Precision._ The intraday and interday precision of the proposed method was determined by estimating the corresponding responses five times on the same day and on five different days over a period of one week for three different concentrations of SAL (200, 400, 600 ng/spot) and GUA (10, 20, 30  µg/spot). The repeatability of sample application was checked by repeatedly measuring the area of seven spots having same concentration of SAL (400ng/spot) and GUA (20  µg/spot) applied on the same plate, while the repeatability of measurement of peak area was checked by repeatedly measuring the area of one spot of SAL (400ng/spot) and GUA (20  µg/spot) for seven times. The results were reported in terms of RSD. (d) LOD and LOQ._ The LOD and LOQ of SAL and GUA were calculated by preparing a series of solutions containing decreasing concentrations of SAL from 0.02 to 0.004 mg/ml and GUA from 1 to 0.001 mg/ml by appropriate dilution of the stock solutions of these drugs (SAL 0.02 mg/ml and GUA 1 mg/ml). (e) Robustness._ The robustness of the method was studied by changing the composition of the mobile phase by  ± 0.2 mL of organic solvent, development distance by  ±1 cm, and temperature by  ± 2ËÅ ¡C. Determination of SAL and GUA in Liquid Dosage Form The responses of sample solutions were measured at 280 nm for quantification of SAL and GUA by the proposed method. The amount of SAL and GUA present in the sample solutions were determined by fitting the responses into the regression equation of the calibration curve for SAL and GUA, respectively. RESULT AND DISCUSSION Since both SAL and GUA have nearly same wavelength maxima, interference becomes prominent in UV-Visible spectrophotometry. Also the estimation of any component at its null point is not that much reliable as the estimation at maximum wavelength. Consecutively for highly specific methods like HPLC and HPTLC, physical separation of those substances is usually necessary before quantitative determination of those substances. So, attempt has been made to develop a validated separation technique for the separation of SAL and GUA in the mixture by HPTLC. The chromatographic conditions were adjusted in order to obtain an efficient and simple routine method. Different mobile phases were tried for the separation of the above substances. The optimized solvent system was Ethyl acetate: methanol: ammonia (25 %w/v) (7.5:1.5:1;v/v/v). The Rf values were found to be 0.47 for SAL and 0.65 for GUA. (Figure 2) The maximum wavelength of SAL was found to be 279nm-280nm and the maximum wavelength of GUA was 274nm-275nm. As both compounds have nearly same ÃŽ » max, 280 nm was selected for simultaneous scanning of SAL and GUA. In this way, SAL can be detected at low concentrations in the presence of GUA at high concentrations. Preparation of calibration curve As the concentration range of SAL is from 200 to 1000 ng, direct proportionality (linearity) of the concentration with its absorbance was obtained. Linear regression analysis is applied to analyze calibration curve of SAL. The equation is y = 3.659x + 409.8 (Figure 2) With the objective to allow simultaneous analysis by developing method in wider concentration range, non-linear regression analysis mode was utilized for estimation of GUA. Polynomial regression mode is applicable if wide concentration ranges (1:50 to 1:100) are worked out and with high amount of substance measured in non-linear detector range. The equation for calculation is y = -4.207x2 + 578.12x + 9343.48 (Figure 3) Method Validation Specificity._ The excipients present in the liquid dosage form did not interfere with the chromatographic responses of SAL and GUA as the peak purities r(S, M) = 0.997 and r (M, E) = 0.9996 for SAL and r(S, M) = 0.997 and r(M,E) = 0.9996 for GUA. Also, good correlation (r= 0.9999 for SAL and 0.9998 for GUA) were obtained between standard and sample spectra. Accuracy._ The mean recoveries obtained for SAL and GUA were 100.07 ± 0.49% and 100.04  ± 0.63% RSD , respectively. The accuracy results are shown in Table 2 Precision._ The values of RSD for intraday and interday variations were found to be in the range of 2.56-4.57% and 2.67-4.46% for SAL and 1.95-4.20% and 2.39-4.42% for GUA. RSD for repeatability of sample application were found to be 1.86 and 1.48 for SAL and GUA respectively, while the repeatability of peak area measurement was 0.47 and 0.18% for SAL and GUA respectively. LOD and LOQ._ The LOD and LOQ were 70 and 100 ng for SAL and 30 and 50 ng for GUA. Robustness._ The method was found to be robust, as the results were not significantly affected by deliberate but slight variation in the method parameters. Determination of SAL and GUA in Liquid Dosage Form The proposed HPTLC method was applied successfully for the determination of SAL and GUA in liquid dosage form. The results obtained for SAL and GUA were comparable with the corresponding labeled claim values. (Table 4) CONCLUSIONS Due to the absence of an official method for this binary mixture, the high-performance thin layer chromatographic method proposed in this article could represent an alternative to chemo metrics-assisted spectrophotometry, Electro kinetic chromatography and Gas chromatography-Mass spectrometry previously published. This method has been validated for linearity, precision, accuracy, and specificity, and has proved to be convenient and effective for the quality control of SAL and GUA in marketed syrups, with out any interference of excipients. ACKNOWLEDGEMENTS: We are thankful to the principal, L.M. College of Pharmacy for providing us the facility for successful completion of our project. REFERENCES 1.Klaus Flory, H. G. B. in Analytical Profiles of Drug Sunstances and Excipients, Vol. 25, pp. 121, Acedemic Press, Inc. 2.(1996) The Indian Pharmacopoeia, The Manager of Publication, Delhi. 3.Parfitt, K. (Ed.) (1999) Martindale The Complete Drug Reference, The Pharmaceutical Press, UK, The Pharmaceutical Press, UK. 4.(2007) The British Pharmacopoiea, Department of Health on behalf of the Health Ministers, London. 5.(2007) The United States Pharmacopoiea-30 NF-25. 6.El-Gindy, A., Emara, S., and Shaaban, H. (2007) J. Pharm. Biomed. Anal. 43, 973-82. 7.Pomponio, R., Gotti, R., and Hudaib, M. J. Sep. Sci. 24, 258 264. 8.D., N. L., Quiming, N. S., and Saito, Y. (2009) J. Liq. Chromatogr. Related Technol. 32, 1407 1422 9.International Conference on Harmonization (2005) Validation of Analytical Procedure Methodology (Q2R1), Technical Requirements for Registration of Pharmaceuticals for Human Use, Geneva, Switzerland Table 1. Data indicating various validation parameters of the developed method Table 2. Results of precision study for SAL and GUA determination by the proposed HPTLC method a Repeatability of sample application. b Repeatability of measurement of peak area. Table 3. Data for the recovery study of SAL and GUA Table 4. Analysis results for SAL and GUA liquid dosage forms by the proposed HPTLC methods (n=5) Figure 1. Chemical Structures of (a) SAL and (b) GUA Figure 2. Calibration curve of SAL Figure 3. Calibration curve of GUA Figure 4. (a) HPTLC chromatogram showing separation of SAL and GUA in their combined standard solution at 280 nm , with Rf 0.47 and 0.65, respectively. (b) Chromatogram showing the separation of SAL and GUA in Ventorlin Syrup. Figure 5. (a) HPTLC chromatogram showing separation of SAL and GUA in their combined standard solution at 280 nm , with Rf 0.47 and 0.65, respectively. (b) Chromatogram showing the separation of SAL and GUA in Asthalin Syrup.

Thursday, September 19, 2019

Motivation and Conflict Management Essay -- Workplace

Motivation and Conflict Management Organizations strive for creative ways to enhance employee motivation and resolve conflicts with the desire to have employees perform better within the workplace. To motivate one has to be motivated. Motivation within the workplace has to be constant and requiring a goal. Motivation, if not repeated will not last. Therefore, learning to determine how different organizations apply motivation theories to motivate employees, analyzing conflict management strategies and what approaches work best in different organizations will influence the success of an organization. Motivation Theories and Organizational Behavior Motivation is the concept of stimulating or arousing a person to achieve a goal. Motivation has much to do with desire and ambition, and if they are absent, motivation is absent too (What is Motivation and How to Strengthen It, para. 1). Motivation theories are unique to each organization. Some organizations have come up with motivation theories such as setting work goals, job performance evaluations, and fair treatment policies within the work environment to keep employees motivated. The impact that individuals, groups and structures have on behavior within organizations is Organizational Behavior. Motivation is affected by organizational behaviors, which is why different organizations apply motivation theories to motivate employees. Applying Motivation Theories to Motivate Employees Keeping workers motivated in today workplace can be not just a job, but also an adventure. In many organizations this is a challenge because the workplace is made up of a diverse cultural environment. Managers are still the driving force for any business and the responsibility and demand to ac... ...ional behavior. Team B was able to discuss and analyze different conflict strategies used in the workplace. The research educates Team B to how organizations implement various theories and strategies in accordance with their work environments. Works Cited Lewis, Clive (2007) Human resource management international digest. Bradford: 2007. Vol 15, Iss.4: pg. 3. Sasson, R. (2001-2010). SuccessConsciousness.com. Retrieved from http://www.successconsciousness.com/strengthen_motivation.htm Swinton, Lyndsay (2006). Workplace Conflict Management: Strategy for Successful Resolution. Retrieved November 14, 2010 from http://www.mftrou.com/workplace-conflict-management-strategy.html John R. Schermerhorn, James G. Hunt, Richard N. Osborn (2008). Organizational Behavior 10th ED. Retrieved November 12, 2010 from Academic Search Motivation and Conflict Management Essay -- Workplace Motivation and Conflict Management Organizations strive for creative ways to enhance employee motivation and resolve conflicts with the desire to have employees perform better within the workplace. To motivate one has to be motivated. Motivation within the workplace has to be constant and requiring a goal. Motivation, if not repeated will not last. Therefore, learning to determine how different organizations apply motivation theories to motivate employees, analyzing conflict management strategies and what approaches work best in different organizations will influence the success of an organization. Motivation Theories and Organizational Behavior Motivation is the concept of stimulating or arousing a person to achieve a goal. Motivation has much to do with desire and ambition, and if they are absent, motivation is absent too (What is Motivation and How to Strengthen It, para. 1). Motivation theories are unique to each organization. Some organizations have come up with motivation theories such as setting work goals, job performance evaluations, and fair treatment policies within the work environment to keep employees motivated. The impact that individuals, groups and structures have on behavior within organizations is Organizational Behavior. Motivation is affected by organizational behaviors, which is why different organizations apply motivation theories to motivate employees. Applying Motivation Theories to Motivate Employees Keeping workers motivated in today workplace can be not just a job, but also an adventure. In many organizations this is a challenge because the workplace is made up of a diverse cultural environment. Managers are still the driving force for any business and the responsibility and demand to ac... ...ional behavior. Team B was able to discuss and analyze different conflict strategies used in the workplace. The research educates Team B to how organizations implement various theories and strategies in accordance with their work environments. Works Cited Lewis, Clive (2007) Human resource management international digest. Bradford: 2007. Vol 15, Iss.4: pg. 3. Sasson, R. (2001-2010). SuccessConsciousness.com. Retrieved from http://www.successconsciousness.com/strengthen_motivation.htm Swinton, Lyndsay (2006). Workplace Conflict Management: Strategy for Successful Resolution. Retrieved November 14, 2010 from http://www.mftrou.com/workplace-conflict-management-strategy.html John R. Schermerhorn, James G. Hunt, Richard N. Osborn (2008). Organizational Behavior 10th ED. Retrieved November 12, 2010 from Academic Search

Wednesday, September 18, 2019

What Doth A Leader Make? :: essays research papers

<a href="http://www.geocities.com/vaksam/">Sam Vaknin's Psychology, Philosophy, Economics and Foreign Affairs Web Sites How come a leader becomes a leader? In this article, we are not interested in the historical process but in the answer to the twin questions: what qualifies one to be a leader and why do people elect someone specific to be a leader. The immediately evident response would be that the leader addresses or is judged by his voters to be capable of addressing their needs. These could be economic needs, psychological needs, or moral needs. In all these cases, the needs are judged to be serious enough as to threaten acceptable existence (emphasis on the word â€Å"acceptable†). Mere survival is rarely at risk (famine, war, plague). On the contrary, people are mostly willing to sacrifice their genetic and biological survival on the altar of acceptable existence. To be acceptable, life must be honourable. To be honourable, certain conditions (commonly known as â€Å"rights†) must be fulfilled and upheld. No life can be honourable without food and shelter (property rights), person al autonomy (as safeguarded by freedoms), security, respect (as expressed through human rights) and influence upon the future (civil rights). In the absence of even one of these elements, people tend to gradually become convinced that their lives are not worth living. They become mutinous and try to restore the â€Å"honourable equilibrium†. They seek food and shelter by inventing new technologies and by implementing them in a bid to control nature and other, human, factors. They rebel against any massive breach of their freedoms : free speech has provoked more bloodshed than it has ever prevented. The seek security : they legislate and create law enforcement agencies and form an army. Above all, people are concerned with being respected and with influencing their terms of existence, present and future. The two may be linked : the more able a person is to influence his environment, to mould it – the more respected he is by others. Leaders are perceived to be possessed of qualities conducive to the success of such battles of restoration. Some signal that the leader emits keeps telling his followers : I can increase your chances to win the war that you are waging in order to find food and shelter / respect / personal autonomy / security / an enhanced ability to influence your future. But WHAT is this signal? What information does it carry with it?

Tuesday, September 17, 2019

Religion and Morality Essay

Morality as dependant on religion The idea of whether morality and religion are linked or not was first looked upon by Plato, where in his Euthyphro Dilemma he asks, ‘Is what is pious loved by the Gods because it is pious, or is something pious because it is loved?’ In other words he is questioning whether things are good because God commands them to be, or does God command them because they are good? I will first examine the view followed by theists today, that things are good because God loves them and that religion and morality are linked. There are a number of ways which you can establish a possible link between religion and morality, the first being heteronomously. Heteronomy is the view that morality depends on religious belief, or things derived from religion. The rules in heteronomous societies are from religious authority so will obviously be linked to religion, however a non-religious person is still capable of being heteronomous as they live and abide by the culture’s laws therefore adopting a morality based on religion. To a certain extent it is hard to deny aspects of heteronomy, since words like ‘good’ and ‘evil’ are shaped by religion. It would be hard to present an ethical theory free from these terms. A theonomous link can also be made, where morality and religion depend on one source (for example, in Western cultures God) who is the fundamental designer of what is moral. Unlike Heteronomy, Theonomy does not require a religious authority as it is to do with the individual’s personal belief in the aforementioned source. The Natural Law theory developed by Aquinas is considered theonomous, in which an uncaused cause is the creative source for all. We can access God directly in this theory by fulfilling our purposes in life set by Him at our creation. The view that things are good through God’s command is directly illustrated in The Divine Command Theory, the common theory adopted by believers in the God of Classical Theism. According to Emil Brunner (1947), ‘The Good consists in always doing what God wills at any particular moment’, as it essentially impossible for God to command an evil act. If nothing was commanded or forbidden by God then there would be no wrong or right and arguably, there would be chaos. The DCT can be seen to provide a strong foundation for a stable necessary morality to be built upon as well as personal reasons to abide by it. For example, taken from the views of Kant (although not directly aimed at the DCT) the belief in the existence of an afterlife gives us incentive to live a moral life, which we otherwise may not be able to force ourselves to do. The presence of such an afterlife, and the fear of punishment make it rational (According to William Craig) to go against your own self-interest for the benefit of others, as self-sacrificial acts are looked upon well by God. This provides more answers to the question ‘Why be Moral?’ The DCT can be accessed through the Decalogue in the Bible (Exodus 20, old Testament), which provides a set of ten absolute, deontological commands by God. Also through the New Testament in Jesus’ ‘Sermon on the Mount’ where he makes laws much more situationalist with teachings such as ‘Love your neighbour’, which are flexible and apply to many situations. Finally, many theists argue that it does not make sense for morals to exist in a non-moral universe as there is nowhere they originate from, they don’t fit into a natural universe. They do however fit into a theistic universe where they were created by a moral creator (i.e God), it is then easy to see why they exist. This is supported by philosophers such as John Newman who states that feelings of responsibility and guilt point to God, and by D.I Trethowan, who suggests that an awareness of obligation is an awareness of God. Aii) Morality as independent from Religion A belief in morality as being totally independant from God is an autonomous belief, and there are many arguments in compliance with Autonomy, very much to do with the idea of free-will. If we really are to act with personal freedom of choice then we cannot act out of fear of God’s punishment, it totally voids the notion of free-will; and if God is omniscient and omnipotent he would know what decisions we are to make anyway and he would have the ability to stop us making the wrong ones. James Rachels concludes that no being like God can exist who requires us to abandon our moral autonomy is worth worshipping. There are theories in concurrence with Autonomy which allow still for a good, firm morality without dependency on religion such as Utilitarianism (greatest good for greatest number) so it can be said that religion is unnecessary There are many autonomous arguments against the DCT, beginning with the fact that God himself is not bound by any moral law. This would mean that God’s Ten Commandments could easily have been totally the opposite to what they are, encouraging acts like murder and we would still consider them to be good as God is the epitemy of good. This worrying problem was recognized by philosophers such as G.W Leibniz, who decreed, ‘Why praise him for what he has done, if he would be equally as praiseworthy if he had done the contrary?’ There is belief that if God had commanded acts such as murder, people still would not do them as we through our intuition feel they are intrinsically wrong. Another difficulty with the DCT lies in the many different interpretations which can be drawn from God. The existence of lots of different religions all with equal claim to God makes it very complicated as we cannot tell which one is right. Also, if morality depends on God then surely it would be impossible for an atheist to live a moral life, but this is obviously untrue as so many atheists do live morally. Further criticisms of the DCT stem from its assumption that God is omnibenevolent, a claim which is not easy to comprehend for the atheist because of the undeniable existence of evil. Lastly, many people argue that religion is itself immoral, as it is through religion that the most part of suicide bomb attacks, and other horrific acts are carried out. Examples could be drawn from the events in America involving the Twin Towers, or more recently the teacher in Sudan who is imprisoned for allowing a teddy to be named after the prophet Muhammad. If not for religion, these arguably ridiculous acts would never be justifiable. Hume said on the subject, ‘the errors in religion are dangerous; those in philosophy only ridiculous. Richard Dawkins in ‘The God Delusion’, clearly advocates the theory that religion is immoral when he discusses the story of Lot. This ‘righteous’ man is to be saved from the destruction of Soddom and Gomorrah because he is the most worthy man, however he offers his daughters for gang rape. According to Dawkins this emphasizes the serious disrespect for women in an intensely religious culture. B) To what extent is one of these claims more convincing than the other Going back to the basics of the Divine Command Theory, there are 613 commands in the Bible which were originally in effect, but are not now because they are ‘outdated’, and theists argue that an omniscient God used them knowing they would be relevant for different times. These theists fail, however to a provide a logical explanation for why there is nothing in the Bible which can be related to biological advances such as cloning, an omniscient God should be capable of filling in these gaps in moral law. Furthermore, as Dawkins relevantly points out – how can someone decide that parts of the Bible are now irrelevant, this is just picking and choosing which parts are in your best interest to follow. This suggests that the Bible and therefore the DCT does not in fact provide a stable foundation for morality as there are numerous conclusions to be drawn from ‘relevant’ parts. It must also be taken into consideration that the Bible is not in its original form, through hundreds of years it has been composed and revised so (as put forward by Dawkins again) does it not seem strange that we base our whole morality on such a distorted teaching. Another feature of the DCT, is that everyone will be judged by God, punished for their sins, often in the form of natural disasters. People could say that the recent tsunami and Hurricane Katrina incidents were a form of punishment, but as Dawkins once again highlights, why did this have to happen? It is hard to believe that everyone who died in these disasters was evil, so why could our omnipotent God of Classical Theism not just strike down the individuals without causing so much collateral damage. Moreover, this persuasively further argues the immoral messages religion can be seen to give. Often, it is argued that the set in stone rules of the DCT inspire people to live a moral life out of the incentive of making it to heaven, and avoiding hell. This may be true, but does it not tarnish the goodness of an act when it is done out of selfish reason? Does it then make that act immoral? Yes it does, so it can then be said that the DCT again fails to provide a stable, reasonable basis for morality. These set in stone rules are also cause for discussion, as they are obviously inarguable to a Divine Command Theorist. To them, consequentialist views such as killing someone to save a greater number would undisputedly be wrong. Even if our intuition is what is telling us that defying a command is right, the believer in DCT would say it is our intuition at fault; They do, however fail to take into consideration that by their own decrees intuition is given to us by God to live morally, so why would we intuitively want to go against God? Dawkins’ arguments suggest that religion is responsible for the most part of evil in the world and his descriptions of people like terrorists as e.g. ‘Not psychotic; they are religious idealists who, by their own lights, are rational’ certainly make sense. However he makes it seem that no religious person has the capacity to do good, which can easily be refuted at the mere mention of the names Mother Theresa, or Martin Luther King. He also unsurprisingly doesn’t mention the likes of atheist like Stalin who birthed communism in Russia. Despite this, the majority of Dawkins views and the massive flaws in the DCT show the latter statement in the initial question (‘Is something good because God commands it, or does God command something because it is good?’) to be the most convincing of the two. Although the DCT offers a way for humanity to be good, religion itself harbors too many inconsistencies to base everything we stand for on.

Monday, September 16, 2019

Effect of Social Opportunity and Anxiety on Academic Achievement Essay

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